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How nerve cells flexibly adapt to acoustic signals

How nerve cells flexibly adapt to acoustic signals

How nerve cells flexibly adapt to acoustic signals: Depending on the input signal, neurons generate action potentials either near or far away from the cell body. Continue reading

Brain cell discovery could open doors to targeted cancer therapies

Brain cell discovery could open doors to targeted cancer therapies

Fresh insights into the processes that control brain cell production could pave the way for treatments for brain cancer and other brain-related disorders. Scientists have gained new understanding of the role played by a key molecule that controls how and when nerve and brain cells are formed — a process that allows the brain to develop and keeps it healthy Continue reading

Development of new cell models that report circadian clock function

Development of new cell models that report circadian clock function

Researchers at the University of Memphis and University of Pennsylvania report the development of robust new liver and fat cell models that report circadian clock function. These models are amenable to high throughput drug screening and could be used to find promising small molecules to resynchronize or help body clocks function normally. The consequences of modern life, eating and staying up later, shift work, cell phone addiction, and travel across time zones, all disturb internal clocks. Continue reading

Taking iron improves women’s exercise performance, study shows

Taking iron improves women’s exercise performance, study shows

A new University of Melbourne study has found that women who take iron supplements, experience a marked improvement in their exercise performance. Continue reading

Immunotherapy could help tackle tough liver cancer

Immunotherapy could help tackle tough liver cancer

Significant new data presented today at the International Liver Congress™ 2014 indicate that liver cancer (Hepatocellular Carcinoma (HCC)) may be treated by adoptive T-cell therapy. This new therapeutic approach in the treatment of HCC could be very important as without treatment the 5 year survival rate is just 5%. Continue reading

Viral hepatitis more deadly than HIV in Europe

Viral hepatitis more deadly than HIV in Europe

Mortality from viral hepatitis is significantly higher than from HIV/AIDS across EU countries, according to results from The Global Burden of Disease Study 2010 (GBD 2010) which was announced for the first time today at the International Liver CongressTM 2014. Continue reading

Positive outcomes for hepatitis C transplant patients

Positive outcomes for hepatitis C transplant patients

New research announced at the International Liver CongressTM 2014 today provides new hope for the notoriously difficult-to-treat population of liver transplant patients with recurring hepatitis C (HCV). As part of a compassionate use program, 104 post-liver transplant patients with recurring HCV who had exhausted all treatment options and had poor clinical prognoses, received sofosbuvir (SOF) and ribavirin (RBV) with pegylated interferon (PEG) included at the physicians’ discretion for up to 48 weeks. Among patients whose clinical outcomes have been reported, 62% achieved SVR12. Continue reading

Young athletes from higher income families more likely to suffer serious overuse injuries

Young athletes from higher income families more likely to suffer serious overuse injuries

A Loyola University Medical Center study is reporting for the first time a link between overuse injury rates in young athletes and their socioeconomic status. The rate of serious overuse injuries in athletes who come from families that can afford private insurance is 68 percent higher than the rate in lower-income athletes who are on public insurance (Medicaid), the study found Continue reading

New drug, molecular insight into triple negative breast cancers

New drug, molecular insight into triple negative breast cancers

Most breast cancers are treated by blocking their addictions, for example depriving estrogen-fueled tumors of estrogen. Continue reading

Yeast provides genetic clues on drug response

Yeast provides genetic clues on drug response

Why do people respond differently to the same drug? For the first time, researchers have untangled genetic and environmental factors related to drug reactions, bringing us a step closer to predicting how a drug will affect us. Researchers at the University of British Columbia exposed 6,000 strains of yeast to 3,000 drugs Continue reading