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Dosage of HIV drug may be ineffective for half of African-Americans

Dosage of HIV drug may be ineffective for half of African-Americans

Many African-Americans may not be getting effective doses of the HIV drug maraviroc, a new study from Johns Hopkins suggests. Continue reading

Sorting cells with sound waves

Sorting cells with sound waves

Researchers from MIT, Pennsylvania State University, and Carnegie Mellon University have devised a new way to separate cells by exposing them to sound waves as they flow through a tiny channel. Their device, about the size of a dime, could be used to detect the extremely rare tumor cells that circulate in cancer patients’ blood, helping doctors predict whether a tumor is going to spread. Separating cells with sound offers a gentler alternative to existing cell-sorting technologies, which require tagging the cells with chemicals or exposing them to stronger mechanical forces that may damage them Continue reading

What can 14th century Venice teach us about Ebola, other emerging threats?

What can 14th century Venice teach us about Ebola, other emerging threats?

The way in which the Italian city of Venice dealt with the outbreak of the plague in the fourteenth century holds lessons on how to even mitigate the consequences of today’s emerging threats, like climate change, terrorism and highly infectious or drug-resistant diseases. So says Dr. Igor Linkov of the US Army Engineer Research and Development Center, and a visiting professor of the Ca Foscari University in Italy Continue reading

Challenges ahead in improving child health by increasing access to sanitation in India

Challenges ahead in improving child health by increasing access to sanitation in India

A study published in this week’s PLOS Medicine on large-scale rural sanitation programs in India highlights challenges in achieving sufficient access to latrines and reduction in open defecation to yield significant health benefits for young children. The researchers, led by Sumeet Patil from the School of Public Health, University of California at Berkeley, and the Network for Engineering and Economics Research and Management in Mumbai, India conducted a cluster randomised controlled trial in 80 rural villages in the Indian state of Madhya Pradesh to measure the effect of India’s Total Sanitation campaign (an initiative to increase access to improved sanitation throughout rural India) on household latrine availability, defecation behaviors, and child health Continue reading

Surgery to repair hip fracture reduces lifetime health care costs by more than $65,000 per patient

Surgery to repair hip fracture reduces lifetime health care costs by more than $65,000 per patient

Each year, more than 300,000 Americans, primarily adults over age 65, sustain a hip fracture, a debilitating injury that can diminish life quality and expectancy, and result in lost work days and substantial, long-term financial costs to patients, families, insurers and government agencies. And while surgery, the primary treatment for hip fractures, successfully reduces mortality risk and improves physical function, little is known about the procedure’s value and return on investment. Continue reading

New statin guidelines an improvement, study shows

New statin guidelines an improvement, study shows

New national guidelines can improve the way statin drugs are prescribed to patients at risk for cardiovascular disease, a Yale University study has found. The research, published Aug. 25 in the Journal of the American College of Cardiology , also showed the new guidelines produce only a modest increase in the number of patients being given the drugs Continue reading

Young driver’s gender linked to crash type, injury severity

Young driver’s gender linked to crash type, injury severity

Gender is often related to what type of severe or fatal crash a young male or young female driver will be involved in, according to a Kansas State University study. The university’s Sunanda Dissanayake, professor of civil engineering, and Niranga Amarasingha, doctoral student in civil engineering, looked at the gender differences and similarities of young drivers involved in all motor vehicle crashes in Kansas across five years. Continue reading

Brain benefits from weight loss following bariatric surgery

Brain benefits from weight loss following bariatric surgery

Weight loss surgery can curb alterations in brain activity associated with obesity and improve cognitive function involved in planning, strategizing and organizing, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism ( JCEM ). Obesity can tax the brain as well as other organs Continue reading

Cancer-fighting drugs might also stop malaria early

Cancer-fighting drugs might also stop malaria early

Scientists searching for new drugs to fight malaria have identified a number of compounds — some of which are currently in clinical trials to treat cancer — that could add to the anti-malarial arsenal. Duke University assistant professor Emily Derbyshire and colleagues identified more than 30 enzyme-blocking molecules, called protein kinase inhibitors, that curb malaria before symptoms start Continue reading

Exposure to toxins makes great granddaughters more susceptible to stress

Exposure to toxins makes great granddaughters more susceptible to stress

Scientists have known that toxic effects of substances known as endocrine disrupting chemicals (EDCs), found in both natural and human-made materials, can pass from one generation to the next, but new research shows that females with ancestral exposure to EDC may show especially adverse reactions to stress. Continue reading