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Gene increases risk of breast cancer to one in three by age 70

Gene increases risk of breast cancer to one in three by age 70

Breast cancer risks for one of potentially the most important genes associated with breast cancer after the BRCA1/2 genes are today reported in the New England Journal of Medicine . Continue reading

Nasal test developed for to diagnose Creutzfeldt-Jakob disease

Nasal test developed for to diagnose Creutzfeldt-Jakob disease

A nasal brush test can rapidly and accurately diagnose Creutzfeldt-Jakob disease (CJD), an incurable and ultimately fatal neurodegenerative disorder, according to a study by National Institutes of Health (NIH) scientists and their Italian colleagues. Continue reading

Increased adoption of complex care management can help meet cost savings, quality goals

Increased adoption of complex care management can help meet cost savings, quality goals

The care of patients with complex medical needs is widely regarded as one of the key factors driving increased U.S. health costs, and it is generally accepted that 10 to 15 percent of Medicare patients account for 65 to 75 percent of all Medicare spending. Many of the country’s leading health care organizations have been adopting the strategy of complex care management — assembling multidisciplinary teams of physicians, nurses, pharmacists, mental health professionals and others, with services being coordinated by care managers who work closely with patients and their family members Continue reading

Stress during pregnancy can be passed down through generations, rat study shows

Stress during pregnancy can be passed down through generations, rat study shows

To better understand problems during pregnancies today, we should look to the experiences of our ancestors, research published in the open access journal BMC Medicine suggests. Scientists investigating pregnancies in four generations of rats show that inherited epigenetic effects of stress could affect pregnancies for generations. Continue reading

Link between vitamin D, dementia risk confirmed

Link between vitamin D, dementia risk confirmed

Vitamin D deficiency is associated with a substantially increased risk of dementia and Alzheimer’s disease in older people, according to the most robust study of its kind ever conducted. An international team, led by Dr David Llewellyn at the University of Exeter Medical School, found that study participants who were severely Vitamin D deficient were more than twice as likely to develop dementia and Alzheimer’s disease. The team studied elderly Americans who took part in the Cardiovascular Health Study Continue reading

Behavior-focused therapies help children with autism, study shows

Behavior-focused therapies help children with autism, study shows

Vanderbilt researchers this week reported updated findings regarding the benefits of behavior-focused therapies for children with autism spectrum disorder (ASD). The review, conducted by the Agency for Healthcare Research and Quality (AHRQ)-funded Vanderbilt Evidence-based Practice Center (EPC), updates a prior systematic review of interventions for children (up to age 12) with a focus on recent studies of behavioral interventions. Study authors said the quality of research studies has improved dramatically since AHRQ’s 2011 review of studies on ASD, when authors reported that there were significant gaps in research available to document the benefits of treatments. Continue reading

Designing embryo transfer policies: What’s at issue?

Designing embryo transfer policies: What’s at issue?

Brenna Anderson, MD, of the Division of Maternal-Fetal Medicine at Women & Infants of Rhode Island and an associate professor of obstetrics and gynecology at The Warren Alpert Medical School of Brown University, has published a commentary in the current issue of BJOG: An International Journal of Obstetrics and Gynaecology, now available online. The commentary is entitled “The time has come to consider neonatal outcomes when designing embryo transfer policies.” Dr. Anderson offers her commentary in response to an article in the same issue by Kamphius et al Continue reading

Most kids with blunt torso trauma can skip the pelvic X-ray

Most kids with blunt torso trauma can skip the pelvic X-ray

Pelvic x-rays ordered as a matter of course for children who have suffered blunt force trauma do not accurately identify all cases of pelvic fractures or dislocations and are usually unnecessary for patients for whom abdominal/pelvic CT scanning is otherwise planned. Continue reading

Molecular competition drives adult stem cells to specialize, study shows

Molecular competition drives adult stem cells to specialize, study shows

Adult organisms ranging from fruit flies to humans harbor adult stem cells, some of which renew themselves through cell division while others differentiate into the specialized cells needed to replace worn-out or damaged organs and tissues. Continue reading

Discovery about wound healing key to understanding cell movement

Discovery about wound healing key to understanding cell movement

Research by a civil engineer from the University of Waterloo is helping shed light on the way wounds heal and may someday have implications for understanding how cancer spreads, as well as why certain birth defects occur. Professor Wayne Brodland is developing computational models for studying the mechanical interactions between cells. In this project, he worked with a team of international researchers who found that the way wounds knit together is more complex than we thought Continue reading