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Single tick bite can pack double pathogen punch

Single tick bite can pack double pathogen punch

People who get bitten by a blacklegged tick have a higher-than-expected chance of being exposed to more than one pathogen at the same time. Continue reading

Screening tool may under-report malnutrition risk in hospitalized frail older people

Screening tool may under-report malnutrition risk in hospitalized frail older people

A number of frail, older hospital patients in the UK who are either malnourished or at risk of malnutrition may currently go unreported, according to the findings of a new clinical study. Continue reading

Screening tool may under-report malnutrition risk in hospitalized frail older people

Screening tool may under-report malnutrition risk in hospitalized frail older people

A number of frail, older hospital patients in the UK who are either malnourished or at risk of malnutrition may currently go unreported, according to the findings of a new clinical study. The research, which aimed to investigate and compare the ability to predict malnutrition in a group of frail, older hospital patients using current nutritional risk screening tools, concluded that the gold standard for assessing malnutrition risk in this group may not be the best tool. Continue reading

Rapid diagnostic tests for diagnosis of visceral leishmaniasis: Review completed

Rapid diagnostic tests for diagnosis of visceral leishmaniasis: Review completed

Researchers from the Cochrane Infectious Disease Group, co-ordinated through the editorial base in LSTM, conducted an independent review into the effectiveness of rapid diagnostic tests in diagnosing patients with visceral leishmaniasis (VL), published in The Cochrane Library today. VL (or kala-azar) is caused by a parasite and results in fever, a large spleen and other health problems. It occurs in India, Bangladesh and Nepal, east Africa, the Mediterranean region and Brazil Continue reading

Rapid diagnostic tests for diagnosis of visceral leishmaniasis: Review completed

Rapid diagnostic tests for diagnosis of visceral leishmaniasis: Review completed

Researchers from the Cochrane Infectious Disease Group, co-ordinated through the editorial base in LSTM, conducted an independent review into the effectiveness of rapid diagnostic tests in diagnosing patients with visceral leishmaniasis (VL), published in The Cochrane Library today. VL (or kala-azar) is caused by a parasite and results in fever, a large spleen and other health problems. Continue reading

Neurons get their neighbors to take out their trash

Neurons get their neighbors to take out their trash

Biologists have long considered cells to function like self-cleaning ovens, chewing up and recycling their own worn out parts as needed. But a new study challenges that basic principle, showing that some nerve cells found in the eye pass off their old energy-producing factories to neighboring support cells to be “eaten.” The find, which may bear on the roots of glaucoma, also has implications for Parkinson’s, Alzheimer’s, amyotrophic lateral sclerosis (ALS) and other diseases that involve a buildup of “garbage” in brain cells. Continue reading

Exploring how the nervous system develops

Exploring how the nervous system develops

The circuitry of the central nervous system is immensely complex and, as a result, sometimes confounding. When scientists conduct research to unravel the inner workings at a cellular level, they are sometimes surprised by what they find. Continue reading

Counterterrorism, ethics, and global health

Counterterrorism, ethics, and global health

The surge in murders of polio vaccination workers in Pakistan has made headlines this year, but little attention has been devoted to the ethical issues surrounding the global health impact of current counterterrorism policy and practice. Continue reading

False negative results found in prognostic testing for breast cancer

False negative results found in prognostic testing for breast cancer

A recent study evaluating HER2 testing in a large cohort of women with breast cancer found important limitations in the conventional way HER2 testing is performed in the US and internationally. Dartmouth-Hitchcock Norris Cotton Cancer Center physicians and researchers retested tumor samples from a large group of women and found that 22 out of 530 women had their tumor type incorrectly classified Continue reading

Genetic code for diabetes in Greenland broken by scientists

Genetic code for diabetes in Greenland broken by scientists

A spectacular piece of detective work has mapped a special gene variant among Greenlanders which plays a particularly important role in the development of type 2 diabetes. The results have been published in Nature and can be used to improve prevention and treatment options for those genetically at-risk. In collaboration with Greenland researchers from Steno Diabetes Center and University of Southern Denmark, researchers from the University of Copenhagen have carried out the ground-breaking genetic analysis based on blood samples from 5,000 people or approximately 10% of the modestly-sized population inhabiting an area larger than western Europe Continue reading