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Stroke-fighting drug offers potential treatment for traumatic brain injury

Stroke-fighting drug offers potential treatment for traumatic brain injury

The only drug currently approved for treatment of stroke’s crippling effects shows promise, when administered as a nasal spray, to help heal similar damage in less severe forms of traumatic brain injury. In the first examination of its kind, researchers Ye Xiong, Ph.D, Zhongwu Liu, Ph.D., and Michael Chopp, Ph.D., Scientific Director of the Henry Ford Neuroscience Institute, found in animal studies that the brain’s limited ability to repair itself after trauma can be enhanced when treated with the drug tPA, or tissue plasminogen activator. Continue reading

Probiotics protect children, pregnant women against heavy metal poisoning

Probiotics protect children, pregnant women against heavy metal poisoning

Yogurt containing probiotic bacteria successfully protected children and pregnant women against heavy metal exposure in a recent study. Working with funding from the Bill and Melinda Gates Foundation, Canadian and Tanzanian researchers created and distributed a special yogurt containing Lactobacillus rhamnosus bacteria and observed the outcomes against a control group Continue reading

Prenatal BPA exposure associated with diminished lung function in children

Prenatal BPA exposure associated with diminished lung function in children

Date: October 6, 2014 Source: The JAMA Network Journals Summary: Prenatal exposure to bisphenol A, a common chemical used in some plastics, appears to be inconsistently associated with diminished lung function and the development of persistent wheeze in children. Prenatal exposure to bisphenol A (BPA, a common chemical used in some plastics) appears to be inconsistently associated with diminished lung function and the development of persistent wheeze in children, write Adam J Continue reading

Effective treatments available for HIV patients not eligible for efavirenz regimens

Effective treatments available for HIV patients not eligible for efavirenz regimens

A new national clinical trial found HIV drug regimens that do not include efavirenz are effective as first-line antiretroviral therapy. Continue reading

Vesicles influence function of nerve cells

Vesicles influence function of nerve cells

Date: October 6, 2014 Source: Universität Mainz Summary: Tiny vesicles containing protective substances that they transmit to nerve cells apparently play an important role in the functioning of neurons. As cell biologists have discovered, nerve cells can enlist the aid of mini-vesicles of neighboring glial cells to defend themselves against stress and other potentially detrimental factors. Continue reading

Cell migration: How it works, how new discovery may inform cancer research

Cell migration: How it works, how new discovery may inform cancer research

During cancer metastasis, immune response cells are moving in a controlled manner through the body. Researchers from the Department of Biomedicine at the University of Basel discovered novel mechanisms of cell migration by observing cells moving on lines of connective tissue. Their results, published in the journal Developmental Cell, could lead to new approaches in combatting cancer metastasis and inflammation Continue reading

Tumors might grow faster at night

Tumors might grow faster at night

They emerge at night, while we sleep unaware, growing and spreading out as quickly as they can. And they are deadly. Continue reading

Vicious cycle in osteoarthritis: Sleep disturbance, pain, depression, disability

Vicious cycle in osteoarthritis: Sleep disturbance, pain, depression, disability

New research confirms that sleep disturbances are linked to pain and depression, but not disability, among patients with osteoarthritis (OA). Continue reading

First pictures of BRCA2 protein show how it works to repair DNA

First pictures of BRCA2 protein show how it works to repair DNA

Scientists have taken pictures of the BRCA2 protein for the first time, showing how it works to repair damaged DNA. Mutations in the gene that encodes BRCA2 are well known for raising the risk of breast cancer and other cancers. Although the protein was known to be involved in DNA repair, its shape and mechanism have been unclear, making it impossible to target with therapies Continue reading

Attacking type 2 diabetes from a new direction with encouraging results

Attacking type 2 diabetes from a new direction with encouraging results

Type 2 diabetes affects an estimated 28 million Americans according to the American Diabetes Association, but medications now available only treat symptoms, not the root cause of the disease. New research from Rutgers shows promising evidence that a modified form of a different drug, niclosamide — now used to eliminate intestinal parasites — may hold the key to battling the disease at its source. The study, led by Victor Shengkan Jin, an associate professor of pharmacology at Rutgers Robert Wood Johnson Medical School, has been published online by the journal Nature Medicine Continue reading