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Novel software application can stratify early-stage non-small cell lung cancer patients

Novel software application can stratify early-stage non-small cell lung cancer patients

Computer-Aided Nodule Assessment and Risk Yield, is a novel software tool developed at Mayo Clinic that can automatically quantitate adenocarcinoma pulmonary nodule characteristics from non-invasive high resolution computed tomography (HRCT) images and stratify non-small cell lung cancer (NSCLC) patients into risk groups that have significantly different disease-free survival outcomes. Continue reading

Designer ‘barrel’ proteins created

Designer ‘barrel’ proteins created

Proteins are long linear molecules that fold up to form well-defined 3D shapes. These 3D molecular architectures are essential for biological functions such as the elasticity of skin, the digestion of food, and the transport of oxygen in blood Continue reading

A gut bacterium that attacks dengue and malaria pathogens and their mosquito vectors

A gut bacterium that attacks dengue and malaria pathogens and their mosquito vectors

Just like those of humans, insect guts are full of microbes, and the microbiota can influence the insect’s ability to transmit diseases. A study published on October 23rd in PLOS Pathogens reports that a bacterium isolated from the gut of an Aedes mosquito can reduce infection of mosquitoes by malaria parasites and dengue virus Continue reading

A gut bacterium that attacks dengue and malaria pathogens and their mosquito vectors

A gut bacterium that attacks dengue and malaria pathogens and their mosquito vectors

Just like those of humans, insect guts are full of microbes, and the microbiota can influence the insect’s ability to transmit diseases. A study published on October 23rd in PLOS Pathogens reports that a bacterium isolated from the gut of an Aedes mosquito can reduce infection of mosquitoes by malaria parasites and dengue virus Continue reading

YEATS protein potential therapeutic target for cancer

YEATS protein potential therapeutic target for cancer

Federal Express® and UPS® are no match for the human body when it comes to distribution. Continue reading

Paper-based synthetic gene networks could enable rapid detection of ebola and other viruses

Paper-based synthetic gene networks could enable rapid detection of ebola and other viruses

Synthetic gene networks hold great potential for broad biotechnology and medical applications, but so far they have been limited to the lab. A study published by Cell Press October 23rd in the journal Cell reveals a new method for using engineered gene circuits beyond the lab, allowing researchers to safely activate the cell-free, paper-based system by simply adding water Continue reading

Thermal paper cash register receipts account for high bisphenol A (BPA) levels  in humans

Thermal paper cash register receipts account for high bisphenol A (BPA) levels in humans

Bisphenol A (BPA) is a chemical that is used in a variety of consumer products, such as water bottles, dental composites and resins used to line metal food and beverage containers, and also is used in thermal paper cash register receipts. Now, research conducted at the University of Missouri is providing the first data that BPA from thermal paper used in cash register receipts accounts for high levels of BPA in humans. Subjects studied showed a rapid increase of BPA in their blood after using a skin care product and then touching a store receipt with BPA Continue reading

Genome editing technique advanced by researchers

Genome editing technique advanced by researchers

Customized genome editing — the ability to edit desired DNA sequences to add, delete, activate or suppress specific genes — has major potential for application in medicine, biotechnology, food and agriculture. Now, in a paper published in Molecular Cell , North Carolina State University researchers and colleagues examine six key molecular elements that help drive this genome editing system, which is known as CRISPR-Cas. NC State’s Dr. Continue reading

Large variation in Cesarean rates across US hospitals

Large variation in Cesarean rates across US hospitals

Cesarean delivery is the most common inpatient surgery in the United States. US cesarean rates increased from 20.7% in 1996 to 32.9% in 2009 but have since stabilized, with 1.3 million American women having had a cesarean delivery in 2011 Continue reading

Large variation in Cesarean rates across US hospitals

Large variation in Cesarean rates across US hospitals

Cesarean delivery is the most common inpatient surgery in the United States. US cesarean rates increased from 20.7% in 1996 to 32.9% in 2009 but have since stabilized, with 1.3 million American women having had a cesarean delivery in 2011. Continue reading