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Prioritizing pregnant women in malaria endemic regions for bed nets from clinics

Prioritizing pregnant women in malaria endemic regions for bed nets from clinics

Donors, Ministries of Health, implementing agencies, and other partners should prioritise providing pregnant women in malaria endemic regions with long-lasting insecticide treated nets (LLINs) through antenatal care clinics to help prevent malaria and its adverse effects on mother and infant, according to experts from the UK and US, writing in this week’s PLOS Medicine . Jenny Hill, from the Liverpool School of Tropical Medicine, and colleagues from the London School of Tropical Medicine and Hygiene, and the Malaria Control and Elimination Program at PATH in Seattle, explain that LLINs are a powerful public health tool to help improve maternal, neonatal, and infant health but that the use of these nets is well below national and international targets. Continue reading

Rapid and durable protection against Ebola virus with new vaccine regimens

Rapid and durable protection against Ebola virus with new vaccine regimens

One shot of an experimental vaccine made from two Ebola virus gene segments incorporated into a chimpanzee cold virus vector (called chimp adenovirus type 3 or ChAd3) protected all four macaque monkeys exposed to high levels of Ebola virus 5 weeks after inoculation, report National Institutes of Health (NIH) scientists and their collaborators. The ability of the ChAd3 Ebola virus vaccine to elicit rapid protection in monkeys is notable as the world health community battles an ongoing Ebola virus disease outbreak in West Africa. Continue reading

Targeting protein-making machinery to stop harmful bacteria

Targeting protein-making machinery to stop harmful bacteria

One challenge in killing off harmful bacteria is that many of them develop a resistance to antibiotics. Continue reading

Each day in hospital raises risk of multidrug-resistant infection

Each day in hospital raises risk of multidrug-resistant infection

If a patient contracts an infection while in the hospital, each day of hospitalization increases by 1% the likelihood that the infection will be multidrug-resistant, according to research presented at the 54th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) an infectious disease meeting of the American Society for Microbiology. Researchers from the Medical University of South Carolina gathered and analyzed historical data from 949 documented cases of Gram-negative infection at their academic medical center Continue reading

New antifungal as effective as existing drugs with fewer adverse events

New antifungal as effective as existing drugs with fewer adverse events

A newly developed antifungal, isavuconazole, is as effective as an existing drug, voriconazole, against invasive mold disease in cancer patients with less adverse effects, according to phase 3 clinical data presented at the 54th Interscience Conference on Antimicrobial Agents and Chemotherapy, an infectious disease meeting of the American Society for Microbiology. Continue reading

Dynamic duo takes out cellular trash: Research finds how dead cells are removed from body

Dynamic duo takes out cellular trash: Research finds how dead cells are removed from body

In most of the tissues of the body, specialized immune cells are entrusted with the task of engulfing the billions of dead cells that are generated every day. When these garbage disposals don’t do their job, dead cells and their waste products rapidly pile up, destroying healthy tissue and leading to autoimmune diseases such as lupus and rheumatoid arthritis. Continue reading

Past sexual assault triples risk of future assault for college women

Past sexual assault triples risk of future assault for college women

Disturbing news for women on college campuses: a new study from the University at Buffalo Research Institute on Addictions (RIA) indicates that female college students who are victims of sexual assault are at a much higher risk of becoming victims again. In fact, researchers found that college women who experienced severe sexual victimization were three times more likely than their peers to experience severe sexual victimization the following year Continue reading

Novel immunotherapy vaccine decreases recurrence in HER2 positive breast cancer patients

Novel immunotherapy vaccine decreases recurrence in HER2 positive breast cancer patients

A new breast cancer vaccine candidate, (GP2), provides further evidence of the potential of immunotherapy in preventing disease recurrence. This is especially the case for high-risk patients when it is combined with a powerful immunotherapy drug. These findings are being presented by The University of Texas MD Anderson Cancer Center at the 2014 American Society of Clinical Oncology’s Breast Cancer Symposium in San Francisco Continue reading

Synthetic messenger boosts immune system

Synthetic messenger boosts immune system

When a pathogen attacks a healthy cell in the body, T lymphocytes are tasked with identifying and destroying the infected cell. Scientists know that they undergo a “training program” for this task in the lymph nodes or the spleen Continue reading

Rare stem cells hold potential for infertility treatments

Rare stem cells hold potential for infertility treatments

Rare stem cells in testis that produce a biomarker protein called PAX7 help give rise to new sperm cells — and may hold a key to restoring fertility, research by scientists at UT Southwestern Medical Center suggests. Continue reading