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Tag Archives: Study

Cyber buddy is better than ‘no buddy’

Cyber buddy is better than ‘no buddy’

A Michigan State University researcher is looking to give exercise enthusiasts the extra nudge they need during a workout, and her latest research shows that a cyber buddy can help. The study, which appears in the Games for Health Journal , is the first to indicate that although a human partner is still a better motivator during exercise, a software-generated partner also can be effective Continue reading

Male or female? First sex-determining genes appeared in mammals some 180 million years ago

Male or female? First sex-determining genes appeared in mammals some 180 million years ago

Man or woman? Male or female? In humans and other mammals, the difference between sexes depends on one single element of the genome: the Y chromosome Continue reading

Finding safe drugs to treat neurodegenerative diseases

Finding safe drugs to treat neurodegenerative diseases

People diagnosed with Huntington’s disease, most in their mid-thirties and forties, face a devastating prognosis: complete mental, physical, and behavioral decline within two decades. “Mutant” protein clusters, long blamed for the progression of the genetic disease, have been the primary focus of therapies in development by pharmaceutical companies Continue reading

Enzymes that help fix cancer-causing DNA defects disovered

Enzymes that help fix cancer-causing DNA defects disovered

Purdue University researchers have identified an important enzyme pathway that helps prevent new cells from receiving too many or too few chromosomes, a condition that has been directly linked to cancer and other diseases. Mark Hall, associate professor of biochemistry, found that near the end of cell division, the enzyme Cdc14 activates Yen1, an enzyme that ensures any breaks in DNA are fully repaired before the parent cell distributes copies of the genome to daughter cells. Continue reading

Gold nanoparticles help target, quantify breast cancer segments in a living cell

Gold nanoparticles help target, quantify breast cancer segments in a living cell

Purdue University researchers have developed a way to detect and measure cancer levels in a living cell by using tiny gold particles with tails of synthetic DNA. A team led by Joseph Irudayaraj, professor of agricultural and biological engineering, used gold nanoparticles to target and bind to fragments of genetic material known as BRCA1 messenger RNA splice variants, which can indicate the presence and stage of breast cancer. Continue reading

Hundreds of genetic mutations found in healthy blood of a supercentenarian

Hundreds of genetic mutations found in healthy blood of a supercentenarian

Genetic mutations are commonly studied because of links to diseases such as cancer; however, little is known about mutations occurring in healthy individuals. In a study published online in Genome Research , researchers detected over 400 mutations in healthy blood cells of a 115-year-old woman, suggesting that lesions at these sites are largely harmless over the course of a lifetime. Our blood is continually replenished by hematopoietic stem cells that reside in the bone marrow and divide to generate different types of blood cells, including white blood cells Continue reading

Airport security-style technology could help doctors decide on stroke treatment

Airport security-style technology could help doctors decide on stroke treatment

A new computer program could help doctors predict which patients might suffer potentially fatal side-effects from a key stroke treatment. The program, which assesses brain scans using pattern recognition software similar to that used in airport security and passport control, has been developed by researchers at Imperial College London. Results of a pilot study funded by the Wellcome Trust, which used the software are published in the journal Neuroimage Clinical Continue reading

Fat metabolism in animals altered to prevent most common type of heart disease

Fat metabolism in animals altered to prevent most common type of heart disease

Working with mice and rabbits, Johns Hopkins scientists have found a way to block abnormal cholesterol production, transport and breakdown, successfully preventing the development of atherosclerosis, the main cause of heart attacks and strokes and the number-one cause of death among humans. The condition develops when fat builds inside blood vessels over time and renders them stiff, narrowed and hardened, greatly reducing their ability to feed oxygen-rich blood to the heart muscle and the brain. In a series of experiments, described April 7 in the journal Circulation , the Johns Hopkins team says it identified and halted the action of a single molecular culprit responsible for a range of biological glitches that affect the body’s ability to properly use, transport and purge itself of cholesterol — the fatty substance that accumulates inside vessels and fuels heart disease Continue reading

Life stressors trigger neurological disorders, researchers find

Life stressors trigger neurological disorders, researchers find

When mothers are exposed to trauma, illness, alcohol or other drug abuse, these stressors may activate a single molecular trigger in brain cells that can go awry and activate conditions such as schizophrenia, post-traumatic stress disorder and some forms of autism. Until now, it has been unclear how much these stressors have impacted the cells of a developing brain. Past studies have shown that when an expectant mother exposes herself to alcohol or drug abuse or she experiences some trauma or illness, her baby may later develop a psychiatric disorder, including some forms of autism or post-traumatic stress disorder, later in life. Continue reading

Edible flowers may inhibit chronic diseases

Edible flowers may inhibit chronic diseases

A new study in the Journal of Food Science , published by the Institute of Food Technologists (IFT), found that common edible flowers in China are rich in phenolics and have excellent antioxidant capacity. Edible flowers, which have been used in the culinary arts in China for centuries, are receiving renewed interest. Flowers can be used as an essential ingredient in a recipe, provide seasoning to a dish, or simply be used as a garnish. Continue reading