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Tag Archives: Vascular

Polyphenols could yield small benefit for people with PAD

Polyphenols could yield small benefit for people with PAD

In a small study, people with artery problems in their legs walked a little longer and farther when they ate dark chocolate — a food rich in polyphenols, according to new research in Journal of the American Heart Association . Peripheral artery disease (PAD) is a narrowing of the peripheral arteries to the legs, stomach, arms, and head — most commonly in the arteries of the legs. Continue reading

Signals found that recruit host animals’ cells, enabling breast cancer metastasis

Signals found that recruit host animals’ cells, enabling breast cancer metastasis

Working with mice, Johns Hopkins researchers report they have identified chemical signals that certain breast cancers use to recruit two types of normal cells needed for the cancers’ spread. Continue reading

Novel marker, possible therapeutic target for cardiovascular calcification identified

Novel marker, possible therapeutic target for cardiovascular calcification identified

Cardiovascular calcification (deposits of minerals in heart valves and blood vessels) is a primary contributor to heart disease, the leading cause of death among both men and women in the United States according the Centers for Disease Control and Prevention (CDC). “Unfortunately, there currently is no medical treatment for cardiovascular calcification, which can lead to acute cardiovascular events, such as myocardial infarction and stroke, as well as heart failure,” says Elena Aikawa, MD, PhD, Director of the Vascular Biology Program at the Center for Interdisciplinary Cardiovascular Sciences at Brigham and Women’s Hospital (BWH) and Associate Professor of Medicine at Harvard Medical School. Continue reading

Novel marker, possible therapeutic target for cardiovascular calcification identified

Novel marker, possible therapeutic target for cardiovascular calcification identified

Cardiovascular calcification (deposits of minerals in heart valves and blood vessels) is a primary contributor to heart disease, the leading cause of death among both men and women in the United States according the Centers for Disease Control and Prevention (CDC). “Unfortunately, there currently is no medical treatment for cardiovascular calcification, which can lead to acute cardiovascular events, such as myocardial infarction and stroke, as well as heart failure,” says Elena Aikawa, MD, PhD, Director of the Vascular Biology Program at the Center for Interdisciplinary Cardiovascular Sciences at Brigham and Women’s Hospital (BWH) and Associate Professor of Medicine at Harvard Medical School Continue reading

Diabetes distresses bone marrow stem cells by damaging their microenvironment

Diabetes distresses bone marrow stem cells by damaging their microenvironment

Jan. 31, 2013 — New research has shown the presence of a disease affecting small blood vessels, known as microangiopathy, in the bone marrow of diabetic patients. While it is well known that microangiopathy is the cause of renal damage, blindness and heart attacks in patients with diabetes, this is the first time that a reduction of the smallest blood vessels has been shown in bone marrow, the tissue contained inside the bones and the main source of stem cells. Continue reading

Plvap/PV1 critical to formation of the diaphragms in endothelial cells

Plvap/PV1 critical to formation of the diaphragms in endothelial cells

Jan. 3, 2013 — Dartmouth scientists have demonstrated the importance of the gene Plvap and the structures it forms in mammalian physiology in a study published in December by the journal Developmental Cell Continue reading

Study questions technique to repair ruptured abdominal aortic aneurysms

Study questions technique to repair ruptured abdominal aortic aneurysms

ScienceDaily (Aug. 27, 2012) — A new study raises a cautionary note about the increasing use of a minimally invasive procedure to repair ruptured abdominal aortic aneurysms, according to vascular surgeon Dr. Jae Sung Cho of Loyola University Medical Center. Continue reading

Adolescent smokers have artery damage

Adolescent smokers have artery damage

ScienceDaily (Aug. Continue reading

Kawasaki disease in childhood linked to increased risk of adult heart disease

Kawasaki disease in childhood linked to increased risk of adult heart disease

ScienceDaily (July 17, 2012) — Cedars-Sinai researchers have linked Kawasaki Disease, a serious childhood illness that causes inflammation of blood vessels throughout the body, with early-onset and accelerated atherosclerosis, a leading cause of heart disease in adults. In a study published in the August 2012 print edition of Arteriosclerosis, Thrombosis, and Vascular Biology , an American Heart Association peer-reviewed medical journal, a team of researchers showed how Kawasaki Disease in young mice predisposed them to develop accelerated atherosclerosis, often called hardening of the arteries, in young adulthood. The study also suggests that aggressive early treatment of the blood vessel inflammation caused by Kawasaki Disease may reduce the future risk of developing accelerated atherosclerosis. Continue reading

Kawasaki disease in childhood linked to increased risk of adult heart disease

Kawasaki disease in childhood linked to increased risk of adult heart disease

ScienceDaily (July 17, 2012) — Cedars-Sinai researchers have linked Kawasaki Disease, a serious childhood illness that causes inflammation of blood vessels throughout the body, with early-onset and accelerated atherosclerosis, a leading cause of heart disease in adults. In a study published in the August 2012 print edition of Arteriosclerosis, Thrombosis, and Vascular Biology , an American Heart Association peer-reviewed medical journal, a team of researchers showed how Kawasaki Disease in young mice predisposed them to develop accelerated atherosclerosis, often called hardening of the arteries, in young adulthood. The study also suggests that aggressive early treatment of the blood vessel inflammation caused by Kawasaki Disease may reduce the future risk of developing accelerated atherosclerosis. Continue reading