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Tag Archives: Virus

Dosage of HIV drug may be ineffective for half of African-Americans

Dosage of HIV drug may be ineffective for half of African-Americans

Many African-Americans may not be getting effective doses of the HIV drug maraviroc, a new study from Johns Hopkins suggests. Continue reading

Protein’s ability to inhibit HIV release discovered

Protein’s ability to inhibit HIV release discovered

A family of proteins that promotes virus entry into cells also has the ability to block the release of HIV and other viruses, University of Missouri researchers have found. “This is a surprising finding that provides new insights into our understanding of not only HIV infection, but also that of Ebola and other viruses,” said Shan-Lu Liu, MD, PhD, associate professor in the MU School of Medicine’s Department of Molecular Microbiology and Immunology. The study was recently published in the Proceedings of the National Academy of Sciences Continue reading

When a health risk is close to home, health care professionals base their positions on vaccines on their own emotions, personal experiences

When a health risk is close to home, health care professionals base their positions on vaccines on their own emotions, personal experiences

When a health risk gets closer to home, health care professionals base their positions on vaccines more on emotions and personal experiences than on scientific and analytical knowledge, according to a new study by the School of Public Health at the University of Haifa. Continue reading

The marmoset animal model recapitulates disease symptoms of MERS infection in humans

The marmoset animal model recapitulates disease symptoms of MERS infection in humans

An article published on August 21st in PLOS Pathogens reports the first animal model that recapitulates the severe and sometimes lethal respiratory symptoms seen in human patients and suggests that the common marmoset will play an important role in the development effective countermeasures against Middle East respiratory syndrome corona virus. Recent studies had identified how the MERS-CoV recognizes and invades human cells: its spike protein binds to DPP4, a protein on the surface of human cells, and this leads to internalization of the virus which then takes over the human cell and turns it into a virus factory. Continue reading

New shock-and-kill approach could eradicate barrier to curing HIV

New shock-and-kill approach could eradicate barrier to curing HIV

Despite tremendous progress in combatting HIV-1 infection with antiretroviral therapy, there is still no cure for the disease because these drugs do not kill a hidden reservoir of infected cells in the body. Continue reading

Vaccine alternative protects mice against malaria

Vaccine alternative protects mice against malaria

A study led by Johns Hopkins Bloomberg School of Public Health researchers found that injecting a vaccine-like compound into mice was effective in protecting them from malaria. The findings suggest a potential new path toward the elusive goal of malaria immunization. Mice injected with a virus genetically altered to help the rodents create an antibody designed to fight the malaria parasite produced high levels of the anti-malaria antibody. Continue reading

Editing HPV’s genes to kill cervical cancer cells

Editing HPV’s genes to kill cervical cancer cells

Researchers have hijacked a defense system normally used by bacteria to fend off viral infections and redirected it against the human papillomavirus (HPV), the virus that causes cervical, head and neck, and other cancers. Using the genome editing tool known as CRISPR, the Duke University researchers were able to selectively destroy two viral genes responsible for the growth and survival of cervical carcinoma cells, causing the cancer cells to self-destruct. The findings, appearing online August 7 in the Journal of Virology , give credence to an approach only recently attempted in mammalian cells, and could pave the way toward antiviral strategies targeted against other DNA-based viruses like hepatitis B and herpes simplex Continue reading

Editing HPV’s genes to kill cervical cancer cells

Editing HPV’s genes to kill cervical cancer cells

Researchers have hijacked a defense system normally used by bacteria to fend off viral infections and redirected it against the human papillomavirus (HPV), the virus that causes cervical, head and neck, and other cancers. Using the genome editing tool known as CRISPR, the Duke University researchers were able to selectively destroy two viral genes responsible for the growth and survival of cervical carcinoma cells, causing the cancer cells to self-destruct. The findings, appearing online August 7 in the Journal of Virology , give credence to an approach only recently attempted in mammalian cells, and could pave the way toward antiviral strategies targeted against other DNA-based viruses like hepatitis B and herpes simplex. Continue reading

West Africa erects Ebola blockades

West Africa erects Ebola blockades

unable to retrieve full-text contentLiberian soldiers set up an Ebola blockade for the capital as troops in Sierra Leone seal off two districts to stop the virus spreading. Continue reading

Promising Ebola virus treatment development: Crucial research conducted to advance medicine

Promising Ebola virus treatment development: Crucial research conducted to advance medicine

Laboratories at The Scripps Research Institute (TSRI) are investigating antibodies to fight Ebola virus, including the three antibodies recently used to treat two American health care workers infected with the Ebola virus. Continue reading