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Gene therapy reprograms scar tissue in damaged hearts into healthy heart muscle

Gene therapy reprograms scar tissue in damaged hearts into healthy heart muscle

Jan. 4, 2013 — A cocktail of three specific genes can reprogram cells in the scars caused by heart attacks into functioning muscle cells, and the addition of a gene that stimulates the growth of blood vessels enhances that effect, said researchers from Weill Cornell Medical College, Baylor College of Medicine and Stony Brook University Medical Center in a report that appears online in the Journal of the American Heart Association .

Scientists decode ‘software’ instructions of aggressive leukemia cells

Scientists decode ‘software’ instructions of aggressive leukemia cells

ScienceDaily (Oct. 29, 2012) — A team of national and international researchers, led by Weill Cornell Medical College scientists, have decoded the key “software” instructions that drive three of the most virulent forms of acute lymphoblastic leukemia (ALL). They discovered ALL’s “software” is encoded with epigenetic marks, chemical modifications of DNA and surrounding proteins, allowing the research team to identify new potential biomarkers and therapeutic targets

Scientists decode ‘software’ instructions of aggressive leukemia cells

Scientists decode ‘software’ instructions of aggressive leukemia cells

ScienceDaily (Oct. 29, 2012) — A team of national and international researchers, led by Weill Cornell Medical College scientists, have decoded the key “software” instructions that drive three of the most virulent forms of acute lymphoblastic leukemia (ALL). They discovered ALL’s “software” is encoded with epigenetic marks, chemical modifications of DNA and surrounding proteins, allowing the research team to identify new potential biomarkers and therapeutic targets

Reprogrammed amniotic fluid cells could treat vascular diseases

Reprogrammed amniotic fluid cells could treat vascular diseases

ScienceDaily (Oct.

‘Smoking vaccine’ blocks nicotine

‘Smoking vaccine’ blocks nicotine

27 June 2012 Last updated at 14:00 ET By James Gallagher Health and science reporter, BBC News Smokers could one day be immunised against nicotine so they gain no pleasure from the habit, according to researchers in the US.

New vaccine for nicotine addiction

New vaccine for nicotine addiction

ScienceDaily (June 27, 2012) — Researchers at Weill Cornell Medical College have developed and successfully tested in mice an innovative vaccine to treat nicotine addiction. In the journal Science Translational Medicine , the scientists describe how a single dose of their novel vaccine protects mice, over their lifetime, against nicotine addiction

Scientists unravel role of fusion gene in prostate cancer

Scientists unravel role of fusion gene in prostate cancer

ScienceDaily (May 22, 2012) — Share this story on Facebook , Twitter , and Google : Other social bookmarking and sharing tools: Story Source: The above story is reprinted from materials provided by New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College , via EurekAlert!, a service of AAAS. Note: Materials may be edited for content and length.

How cancer cells change once they spread to distant organs

How cancer cells change once they spread to distant organs

ScienceDaily (Feb. 22, 2012) — Oncologists have known that in order for cancer cells to spread, they must transform themselves so they can detach from a tumor and spread to a distant organ. Now, scientists at Weill Cornell Medical College have revealed critical steps in what happens next — how these cells reverse the process, morphing back into classical cancer that can now grow into a new tumor

When erectile dysfunction isn’t whole story

When erectile dysfunction isn’t whole story

ScienceDaily (Aug. 23, 2011) — For men with erectile dysfunction (ED), 65 percent are unable to have an orgasm and 58 percent have problems with ejaculation, according to new research led by physician-scientists at NewYork-Presbyterian Hospital/Weill Cornell Medical Center

Speed of brain signals clocked: New studies illuminate brain’s complex neurotransmission machinery, point to potential source of problems leading to…

Speed of brain signals clocked: New studies illuminate brain’s complex neurotransmission machinery, point to potential source of problems leading to…

ScienceDaily (June 22, 2011) — Two studies featuring research from Weill Cornell Medical College have uncovered surprising details about the complex process that leads to the flow of neurotransmitters between brain neurons — a dance of chemical messages so delicate that missteps often lead to neurological dysfunction. A recent Nature Neuroscience study led by Dr. Timothy Ryan, professor of biochemistry at Weill Cornell Medical College, demonstrates that individual neurons somehow control the speed by which they recycle synaptic vesicles that store neurotransmitters before they are released.